Santee Cooper Country From boating the wide-open waters of the “Great Lakes of South Carolina” to paddling between cypress and tupelo trees in blackwater creeks, this region attracts anglers, boaters, birdwatchers and swimmers alike. During the day, take your pick from golf courses, nature trails, historic battlegrounds and woodlands hunting, and at night, discover low-key eateries and cultural gems in small towns. LOCAL MUST-SEES CYPRESS GARDENS, Moncks Corner • EDISTO MEMORIAL GARDENS, Orangeburg • FISHEAGLE WILDLIFE TOURS , Santee • SANTEE NATIONAL WILDLIFE REFUGE, Summerton • SUMTER OPERA HOUSE , Sumter Santee State Park, Santee 94