South Carolina Vacation Guide - SC 2025

REGION

From enclaves of art galleries and the energetic nightlife districts of South Carolina’s capital city to nature trails winding through old-growth forests and lakefront adventures — plus three scenic rivers running through it all — this region seamlessly blends big-city culture and outdoor pursuits. See where historic buildings are living new lives as trendy restaurants and breweries, and where quiet tree-lined streets lead you through welcoming neighborhoods.

REGIONAL MUST SEES Timmerman Trail, Cayce | Lake Murray, Chapin | South Carolina State Museum, Columbia | Harbison Theatre at Midlands Technical College, Irmo | Congaree National Park, Hopkins | Hollow Creek Distillery, Leesville | Big Mans Marina, Leesville Newberry Opera House, Newberry | Old Mill Antique Mall, West Columbia

Fun Weekend of COLUMBIA COOL

As the capital city, Columbia effortlessly marries urban vibrancy with the allure of the great outdoors, making it a perfect destination for a family-friendly weekend.

Day 1: Friday

Kick off the weekend with something sweet from The Devine Cinnamon Roll Deli in the posh Devine Street neighborhood. Then, go on a wild adventure at the Riverbanks Zoo & Garden, home to more than 3,000 animals including otters, koalas and gorillas — plus all kinds of sea creatures at its Darnall W. and Susan F. Boyd Aquarium & Reptile Conservation Center.

Day 2: Saturday 

Take in culture and creativity at the Soda City Market, which transforms Main Street into a hub of local vendors. Then stop by The Gourmet Shop in Five Points for freshly baked bread and to-go containers of their famous chicken salad and pimento cheese to enjoy for an afternoon picnic in Sesquicentennial State Park, a 1,419-acre park with wetland boardwalks, scenic lake views, a splash pad and two playgrounds.

In the evening, return to The Vista, Columbia’s arts, dining and entertainment district on the Congaree River. Explore 45-plus restaurants and bars, 60 artists' galleries, specialty shops and a diverse mix of businesses.

Day 3: Sunday 

For brunch or lunch in West Columbia, treat yourself to Hawaiian pineapple bread French Toast at the art-filled Cafe Strudel, or go for brisket chili and slaw-topped hot dogs at the James Beard-nominated City Limits Barbeque. Then, cheer on the Columbia Fireflies baseball team at Segra Park (which offers sensory bags equipped with Puro Sound Labs noise-canceling headphones, fidget tools and other sensory-friendly items).