South Carolina Vacation Guide - SC 2025

From blazing hot to lightly spicy, try these South Carolina-made hot sauces and seasoning blends to bring home a taste of The Palmetto State.

Fort Mill's PuckerButt Pepper Company earned the Guinness World Record for the hottest pepper. Take your meal up a notch with The Reaper… if you dare.

Red Clay Peach Hot Sauce layers sweet peaches with smoky habañero. Try it in one of their recipes on their website.

Lowcountry legend Miss Ezzie was known for her “Ezzie-isms,” and this pick is named after one of them. Miss Ezzie’s Mad as a Wet Hen Hot Sauce will add a slight spice to your table — and a touch of sweetness, too.

With names like Hissy-Fit, you know Lillie’s of Charleston spice rubs have got to be good. Use them in the family’s recipes found on their site, including Lillie’s Carolina BBQ Corn.

Made from cayenne peppers but on the milder side, Charleston’s Own Original Lowcountry Hot Sauce is best on local oysters or grits — or in a Bloody Mary.

Straight out of Spartanburg, the mustard-based Yep! Gold River Buffalo Sauce is perfect on — what else? — wings and ribs.

Chef Darren Campbell’s Palmetto Blend seasoning marries seven spices in rich Gullah tradition. You can use it on anything, but those in the know say sprinkling it on your fries is life-changing.